EDUCATE

CHOLANGIOCARCINOMA AUSTRALASIA

COMPILED BY
Steve Holmes
Email: Steve

Ph: +61415153522
FB Messenger
FB Page Steveholmes

RESEARCH | MUTATIONS | TREATMENT | SURGERY

The role of fibroblast growth factor receptors in tumor development and the frequency at which it occurs.

  • WHAT: FGF + FGFR2
  • WHY: MUTATIONS MATTER
  • HOW: VIDEO

OVERVIEW OF FIBROBLAST GROWTH FACTOR

WHAT IS FGR

FGF IS A SIGNALLING PATHWAY

FGR SIGNALLING PATHWAY

Fibroblast growth factor signalling uses a fibroblast growth factor receptor (FGFR2) during cell cycle and cell division. Fibroblast growth factor acts like a growth hormone that adheres to the fibroblast growth factor receptor (FGFR2) and helps to send the chemical signal inside the cell and activates the required transcription factor through a cell signalling pathway and it finally relay the signal inside the cell nucleus and helps in the transcription of the desired gene the product of which helps in the cell cycle and cell division.

WHAT ARE TUMOUR MARKERS

SOURCE: NIH

A tumor marker is anything present in or produced by cancer cells or other cells of the body in response to cancer or certain benign (noncancerous) conditions that provides information about a cancer, such as how aggressive it is, whether it can be treated with a targeted therapy, or whether it is responding to treatment.

Tumor markers have traditionally been proteins or other substances that are made by both normal and cancer cells but at higher amounts by cancer cells. These can be found in the blood, urine, stool, tumors, or other tissues or bodily fluids of some patients with cancer. Increasingly, however, genomic markers such as tumor gene mutations, patterns of tumor gene expression, and nongenetic changes in tumor DNA, are being used as tumor markers.

Many different tumor markers have been characterized and are in clinical use. Some are associated with only one type of cancer, whereas others are associated with multiple different cancer types. No “universal” tumor marker has been found that can reveal the presence of any type of cancer.

Cancer Tool Kits

Newly Diagnosed?

7 Must Do Steps
Cancer Tool Kits @ www.thepcancertoolkit.com
Cancer Tool Kits

Please help us to

  • EQUIP: Every "Newly Diagnosed Patient" with a Cancer Tool Kit immediately upon diagnosis.
  • EMPOWER: All who are connected or impacted  by one Cancer Diagnosis.
  • CONNECT: Newly Diagnosed Patients and Caregivers to our Globally Community

Ensuring that the Newly Diagnosed Patient are empowered with todays lifesaving information, TODAY!

Help by sharing this link

We need your help and feedback

Please help us improve our content and delivery

Rate this page...


Easy to followHard To followHelpedDid not help

Are you a . . .


PatientCaregiverFamily/FriendDoctorNurseOther

How can we improve this?